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Scientists in 3D printing microfluidics devices used for personalized cancer therapy
Dec 18, 2018

The Massachusetts institute of technology (MIT) researchers have 3D print out a new type of microfluidic device, can simulate the biopsy of the tumor tissue of cancer treatment.3D printing equipment can help clinicians better check individual patients before the use of a single dose response to different treatments.


Human tumor is often used to test certain types of cancer drugs.But these models take weeks to grow, and can't explain individual patient creatures, which will greatly influence the effect of cancer treatment.

Researchers of equipment can be in about one hour for 3D printing, is a slightly larger than a quarter of the chips, there are three cylindrical "chimney" from the surface.Chamber can be used for input and a soothing or immune cells such as immune from the fluid ports, and remove the unwanted bubbles.

A key feature is to use a kind of new biological compatibility resin, can support a biopsy samples of long-term survival.After several months of a large number of resin test, the researchers found Pro3dure GR - 10, it is used mainly for preventing molar tooth guard.

The material is almost as transparent as glass, almost no surface defects, and can be in a very high resolution print.And importantly, the researchers found that it will not have negative effects on cell survival.The team for this kind of resin has carried on the cell toxicity test.After 96 hours, material of the cell is still active.

"When you print other resin materials, they release and cell and mixed with the chemicals to kill them, but this did not happen," a researcher at the laboratory for micro system technology LuisFernandoVelasquez - Garcia said."As far as I know, no other can print material close to this level of inertia, if material does not exist."

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